Therapeutic Potential of Manuka Honey Microbubble Dressing in Wound Management

Abstract This study investigates the antibacterial effects of Manuka honey (MH) microbubbles on Staphylococcus aureus (S. aureus) in wound dressings. MH solutions are passed through a microbubble generator with a high‐density stainless steel mesh nozzle to produce MH‐containing microbubbles, which are then injected into dressings in contact with S. aureus. The experiment examines variables including microbubble particle sizes, dressing types, MH microbubbles consumption, and antibacterial action durations. Statistical analyses are performed on colony survival rates under various conditions. Results indicate that MH microbubble characteristics, MH microbubbles consumption, and action duration indirectly enhance S. aureus elimination, with overall disinfection reaching 86% and some conditions achieving 100% efficacy. The study proposes using MH microbubble dressings for S. aureus elimination, environmental cleaning of affected areas, and shortening dermatitis treatment courses. This approach offers a promising method for enhancing wound care and bacterial control in medical settings.