Dimethyl Fumarate Attenuates Behavioral and Structural Impairments Associated with Brain Ischemia in Rats

Although edaravone improved neurological functions and reduced the size of brain ischemia and cell loss, DMF, especially at higher doses, exerted a more beneficial effect on these parameters. Therefore, DMF could be proposed as a reinforcement to currently conventional therapies.

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Publication Details

Journal
Central Nervous System Agents in Medicinal Chemistry
Published
2025-02-04
DOI
https://doi.org/10.2174/0118715249345683250116080547
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Dimethyl Fumarate Attenuates Behavioral and Structural Impairments Associated with Brain Ischemia in Rats

Masoumeh Emamghoreishi, Mohammad Ali Bakhtiari, Mohammad Reza Namavar, Maryam Khastkhodaei Ardakani
Central Nervous System Agents in Medicinal Chemistry
Neuroinflammation and Neurodegeneration Mechanisms
article

Dimethyl Fumarate Attenuates Behavioral and Structural Impairments Associated with Brain Ischemia in Rats

Masoumeh Emamghoreishi, Mohammad Ali Bakhtiari, Mohammad Reza Namavar, Maryam Khastkhodaei Ardakani
article en

Abstract

Although edaravone improved neurological functions and reduced the size of brain ischemia and cell loss, DMF, especially at higher doses, exerted a more beneficial effect on these parameters. Therefore, DMF could be proposed as a reinforcement to currently conventional therapies.

Central Nervous System Agents in Medicinal ChemistryVol. 26(1)
Shiraz University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 97%
Neuroinflammation and Neurodegeneration Mechanisms
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