Two‐year impact of <scp>COVID</scp>‐19: Longitudinal <scp>MRI</scp> brain changes and neuropsychiatric trajectories
Our findings indicate that complex brain adaptations take place up to 2 years following SARS-CoV-2 infection. Some regions manifest enduring abnormalities while others undergo restitution. The attenuation of radio-clinical associations suggests a compensatory function for these regions, pointing to non-brain intrinsic factors to sustain persistent fatigue.
Authors
- Stella A. Glasmacher (ORCID: https://orcid.org/0000-0003-1165-9153)
- Ana Sofia Costa (ORCID: https://orcid.org/0000-0002-1999-6616)
- Tim J. Hartung (ORCID: https://orcid.org/0000-0002-5929-4643)
- Lars Schlenker (ORCID: https://orcid.org/0009-0004-0197-594X)
- Sandro Romanzetti (ORCID: https://orcid.org/0000-0001-8519-1309)
- Jörg B. Schulz (ORCID: https://orcid.org/0000-0002-8903-0593)
- Ferdinand Binkofski (ORCID: https://orcid.org/0000-0002-6750-943X)
- Sophie Wetz
- Carolin Balloff (ORCID: https://orcid.org/0000-0001-9694-5153)
- Kathrin Reetz (ORCID: https://orcid.org/0000-0002-9730-9228)
- Katia Schwichtenberg
- J. Heine (ORCID: https://orcid.org/0000-0001-5226-6650)
- Christiana Franke (ORCID: https://orcid.org/0000-0002-5609-2472)
- Carsten Finke (ORCID: https://orcid.org/0000-0002-7665-1171)
- Ravi Dadsena
- Julia Walders
- Pia Klabunn
- Christina Krockauer
Institutions
- Forschungszentrum Jülich (DE)
- Humboldt-Universität zu Berlin (DE)
- Düsseldorf University Hospital (DE)
- Kliniken Maria Hilf (DE)
- Jülich Aachen Research Alliance (DE)
- Heinrich Heine University Düsseldorf (DE)
- Charité - Universitätsmedizin Berlin (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1111/pcn.13789
- Citations
- 13
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 18.06
Funders
- RWTH Aachen University