Loss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth
These findings shed further light on the biology of PFA1 ependymoma and the role LDOC1 loss has on the tumor and immunobiology of high-risk pediatric ependymoma.
Authors
- Tzu Phang (ORCID: https://orcid.org/0000-0002-4713-8782)
- Rajeev Vibhakar (ORCID: https://orcid.org/0000-0002-5949-3896)
- Michael Handler (ORCID: https://orcid.org/0000-0001-7958-3162)
- Nicholas K. Foreman (ORCID: https://orcid.org/0000-0003-4848-4801)
- Sujatha Venkataraman (ORCID: https://orcid.org/0000-0002-1512-284X)
- Graziella Ribeiro de Sousa (ORCID: https://orcid.org/0000-0003-1809-8539)
- Nathan Dahl (ORCID: https://orcid.org/0000-0003-2555-1741)
- Andrea M. Griesinger (ORCID: https://orcid.org/0000-0002-2831-1009)
- Elvis Terci Valera (ORCID: https://orcid.org/0000-0002-4434-429X)
- Enrique Grimaldo (ORCID: https://orcid.org/0009-0003-4956-7585)
- Andrew M. Donson (ORCID: https://orcid.org/0000-0003-1153-6911)
- Lays Martin Sobral (ORCID: https://orcid.org/0000-0002-8731-850X)
- Vladimir Amani (ORCID: https://orcid.org/0000-0002-2280-2317)
- Todd C. Hankinson (ORCID: https://orcid.org/0000-0002-6288-9496)
- Jean M. Mulcahy Levy (ORCID: https://orcid.org/0000-0002-3022-4246)
- Annaliese J. Calzadilla (ORCID: https://orcid.org/0009-0006-4441-6712)
- Tian Liu (ORCID: https://orcid.org/0000-0002-1569-2084)
- Kendra Jones
Institutions
- Universidade de São Paulo (BR)
- Morgan Adams Foundation (US)
- Children's Hospital Colorado (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1093/neuonc/noaf029
- Citations
- 1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52