Paroxysmal toothache after drinking: alcohol-induced vasospastic angina

Vasospastic angina is caused by transient abnormal contraction of the coronary arteries. Episodes last for 5-15 minutes and are most common in the late evening and early morning.In some patients with vasospastic angina, attacks occur only on drinking days, several hours after drinking. Alcohol-induced vasospastic angina is thought to be attributable to a functional disorder of vascular smooth muscle caused by acetaldehyde accumulation due to alcohol metabolism or transient coronary artery spasm associated with magnesium deficiency and increased endothelin-1 activity.Vasospastic angina can manifest as pain in the head and neck, teeth, arms and shoulders, and is often accompanied by chest pain. However, toothache can be the only symptom and is often bilateral, as in this case.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2025-02-04
DOI
https://doi.org/10.12890/2025_005170
Citations
2
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
Field-Weighted Citation Impact
2.78
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article

Paroxysmal toothache after drinking: alcohol-induced vasospastic angina

Kosuke Ishizuka, Yoshiyuki Ohira, Mitsuyasu Ohta
2 citations
European Journal of Case Reports in Internal Medicine
Takotsubo Cardiomyopathy and Associated Phenomena
2.78
article

Paroxysmal toothache after drinking: alcohol-induced vasospastic angina

Kosuke Ishizuka, Yoshiyuki Ohira, Mitsuyasu Ohta
article en
2 citations

Abstract

Vasospastic angina is caused by transient abnormal contraction of the coronary arteries. Episodes last for 5-15 minutes and are most common in the late evening and early morning.In some patients with vasospastic angina, attacks occur only on drinking days, several hours after drinking. Alcohol-induced vasospastic angina is thought to be attributable to a functional disorder of vascular smooth muscle caused by acetaldehyde accumulation due to alcohol metabolism or transient coronary artery spasm associated with magnesium deficiency and increased endothelin-1 activity.Vasospastic angina can manifest as pain in the head and neck, teeth, arms and shoulders, and is often accompanied by chest pain. However, toothache can be the only symptom and is often bilateral, as in this case.

European Journal of Case Reports in Internal MedicineVol. 12(3)
St. Marianna University School of Medicine (JP), Yokohama City University (JP)
Openalex Percentile: Top 12%
Takotsubo Cardiomyopathy and Associated Phenomena
2.78
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