SABR vs. SBRT: A New Deal for Radiotherapy Beyond Terminology

Employed shortly after its discovery over a century ago, radiotherapy has become the most effective cancer treatment after surgery. Its utility, however, extends beyond oncology, with proven success in managing non-malignant conditions as well. Over its 120-year history, the evolution of radiotherapy has been driven by two main pillars: radiobiological knowledge—explaining the “how,” “why,” and “when” of its application—and technological advancements, which enable and enhance these principles. Efforts to increase precision, amplify therapeutic effects, shorten treatment duration, and ultimately improve clinical outcomes and patient quality of life are central to translational research in radiation oncology. Stereotactic radiotherapy techniques represent the pinnacle of these ongoing advancements.