ONYCHOMYCOSIS: UNRAVELING THE ROLE OF DERMATOPHYTES IN NAIL INFECTIONS

Objective: This study aimed to identify pathogenic fungi that cause onychomycosis and evaluate their clinical presentations and risk factors to enhance management through precise diagnosis and targeted treatment. Methods: The fungi were identified by macroscopic and microscopic morphological features using techniques such as slide cultures, Potassium Hydroxide (KOH) mounts, culture isolation, and Lacto Phenol Cotton Blue (LPCB) staining. Results: 110 nail clippings from patients clinically suspected of onychomycosis were analyzed; 27 had dermatophytic infections. Toenails were involved in 33.8% of the cases, and Distal and Lateral Subungual Onychomycosis (DLSO) was the primary clinical presentation. Trauma was the most common predisposing factor (19%). Conclusion: This study identified dermatophytes as the prime cause of onychomycosis, chiefly affecting toenails with DLSO as the predominant form, and recognized trauma as a key risk factor. Precise identification using traditional diagnostic methods is crucial for targeted treatment and better patient results.

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Publication Details

Journal
International Journal of Pharmacy and Pharmaceutical Sciences
Published
2025-02-01
DOI
https://doi.org/10.22159/ijpps.2025v17i2.52892
Primary Topic
Nail Diseases and Treatments
Type
article
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article

ONYCHOMYCOSIS: UNRAVELING THE ROLE OF DERMATOPHYTES IN NAIL INFECTIONS

Asmiya Parveen, Sadiya Noor Hajira, Iqbal Ahmed, RAHIL PASHA S. A.
International Journal of Pharmacy and Pharmaceutical Sciences
Nail Diseases and Treatments
article

ONYCHOMYCOSIS: UNRAVELING THE ROLE OF DERMATOPHYTES IN NAIL INFECTIONS

Asmiya Parveen, Sadiya Noor Hajira, Iqbal Ahmed, RAHIL PASHA S. A.
article en

Abstract

Objective: This study aimed to identify pathogenic fungi that cause onychomycosis and evaluate their clinical presentations and risk factors to enhance management through precise diagnosis and targeted treatment. Methods: The fungi were identified by macroscopic and microscopic morphological features using techniques such as slide cultures, Potassium Hydroxide (KOH) mounts, culture isolation, and Lacto Phenol Cotton Blue (LPCB) staining. Results: 110 nail clippings from patients clinically suspected of onychomycosis were analyzed; 27 had dermatophytic infections. Toenails were involved in 33.8% of the cases, and Distal and Lateral Subungual Onychomycosis (DLSO) was the primary clinical presentation. Trauma was the most common predisposing factor (19%). Conclusion: This study identified dermatophytes as the prime cause of onychomycosis, chiefly affecting toenails with DLSO as the predominant form, and recognized trauma as a key risk factor. Precise identification using traditional diagnostic methods is crucial for targeted treatment and better patient results.

International Journal of Pharmacy and Pharmaceutical Sciences
Sri Devaraj Urs Medical College (IN), Fortis Hospital (IN), ESIC Hospital (IN), Bangalore Medical College and Research Institute (IN)
Openalex Percentile: Top 97%
Nail Diseases and Treatments
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