Associations of Lipid-Lowering Drugs With Blood Pressure and Fasting Glucose: A Mendelian Randomization Study
Genetically proxied inhibition of HMGCR was significantly associated with low BP and high fasting glucose, while there was no effect of PCSK9 and NPC1L1 inhibition on BP or fasting glucose.
Authors
- Daoxia Guo (ORCID: https://orcid.org/0000-0002-4537-0705)
- Zhengbao Zhu (ORCID: https://orcid.org/0000-0001-5500-0014)
- Xinyue Chang (ORCID: https://orcid.org/0000-0001-7027-3889)
- Mengyao Shi (ORCID: https://orcid.org/0000-0002-5883-0416)
- Xiaoli Qin (ORCID: https://orcid.org/0000-0001-6404-4836)
- Ouxi Shen
- Lulu Sun
- Yi Liu (ORCID: https://orcid.org/0000-0002-2051-440X)
- Beiping Song
- Quan Yu
- Yu He (ORCID: https://orcid.org/0009-0005-9604-2145)
- Jiawen Fei
Institutions
- Tulane University (US)
- Chinese Center For Disease Control and Prevention (CN)
- Soochow University (CN)
Publication Details
- Journal
- Hypertension
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1161/hypertensionaha.124.23829
- Citations
- 4
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 8.03