BACTERIAL PROFILE, ANTIMICROBIAL SUSCEPTIBILITY PATTERNS, AND ASSOCIATED FACTORS OF COMMUNITY-ACQUIRED PNEUMONIA AMONG ADULT PATIENTS IN SOUTH INDIA: A CROSS-SECTIONAL STUDY

Objective: This study aimed to analyze the bacterial profile, antibiotic sensitivity patterns, and prevalence of multidrug resistance in community-acquired pneumonia patients at a tertiary care hospital in Bangalore, India. Methods: Bacterial isolates were identified using standard microbiological techniques and their antibiotic sensitivity was determined using the Kirby-Bauer disk diffusion method. Results: A total of 215 sputum samples were processed, of which 150 tested positive for bacteria. Klebsiella pneumoniae (32%) was the most common isolate, followed by Acinetobacter spp. (20.66%), and Pseudomonas aeruginosa (16%). Notable antibiotic resistance, particularly against third-generation cephalosporins, was observed, with 17.2% of g-negative isolates exhibiting multidrug resistance, primarily due to Extended-Spectrum Beta-Lactamase (ESBL) production. Conclusion: These findings highlight the need for more effective empirical treatment strategies for CAP.

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Publication Details

Journal
International Journal of Pharmacy and Pharmaceutical Sciences
Published
2025-02-01
DOI
https://doi.org/10.22159/ijpps.2025v17i2.52891
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

BACTERIAL PROFILE, ANTIMICROBIAL SUSCEPTIBILITY PATTERNS, AND ASSOCIATED FACTORS OF COMMUNITY-ACQUIRED PNEUMONIA AMONG ADULT PATIENTS IN SOUTH INDIA: A CROSS-SECTIONAL STUDY

Rahil Pasha S A
International Journal of Pharmacy and Pharmaceutical Sciences
Pneumonia and Respiratory Infections
article

BACTERIAL PROFILE, ANTIMICROBIAL SUSCEPTIBILITY PATTERNS, AND ASSOCIATED FACTORS OF COMMUNITY-ACQUIRED PNEUMONIA AMONG ADULT PATIENTS IN SOUTH INDIA: A CROSS-SECTIONAL STUDY

Rahil Pasha S A
article en

Abstract

Objective: This study aimed to analyze the bacterial profile, antibiotic sensitivity patterns, and prevalence of multidrug resistance in community-acquired pneumonia patients at a tertiary care hospital in Bangalore, India. Methods: Bacterial isolates were identified using standard microbiological techniques and their antibiotic sensitivity was determined using the Kirby-Bauer disk diffusion method. Results: A total of 215 sputum samples were processed, of which 150 tested positive for bacteria. Klebsiella pneumoniae (32%) was the most common isolate, followed by Acinetobacter spp. (20.66%), and Pseudomonas aeruginosa (16%). Notable antibiotic resistance, particularly against third-generation cephalosporins, was observed, with 17.2% of g-negative isolates exhibiting multidrug resistance, primarily due to Extended-Spectrum Beta-Lactamase (ESBL) production. Conclusion: These findings highlight the need for more effective empirical treatment strategies for CAP.

International Journal of Pharmacy and Pharmaceutical Sciences
Sri Devaraj Urs Medical College (IN)
Openalex Percentile: Top 97%
Pneumonia and Respiratory Infections
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