Quantitative profiling of the vaginal microbiota improves resolution of the microbiota-immune axis
Our results suggest that total vaginal bacterial load is at least as strong a predictor of the genital immune milieu as current BV clinical diagnostic tools, supporting exploration of the vaginal bacterial load as a predictor of adverse reproductive and sexual health outcomes. Video Abstract.
Authors
- Bryan A. Coburn (ORCID: https://orcid.org/0000-0003-0150-4510)
- Eric Armstrong (ORCID: https://orcid.org/0000-0002-4530-6631)
- Pauline Ngurukiri
- Sanja Huibner
- Wendy Adhiambo
- Suji Udayakumar (ORCID: https://orcid.org/0000-0001-8115-3735)
- James C.S. Pollock (ORCID: https://orcid.org/0000-0003-4767-9420)
- Rupert Kaul (ORCID: https://orcid.org/0000-0002-1586-4093)
- Sergey Yegorov (ORCID: https://orcid.org/0000-0002-7136-7921)
- Tara Beattie (ORCID: https://orcid.org/0000-0001-9156-7341)
- Rachel Liu (ORCID: https://orcid.org/0000-0002-3997-0325)
- Peter Muthoga
- Erastus Irungu
- Joshua Kimani
Institutions
- University Health Network (CA)
- University of Toronto (CA)
- Toronto General Hospital (CA)
- London School of Hygiene & Tropical Medicine (GB)
- Partners for Health and Development in Africa (KE)
- McMaster University (CA)
Publication Details
- Journal
- Microbiome
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1186/s40168-025-02039-4
- Citations
- 8
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 9.46
Funders
- Canadian Institutes of Health Research