CircHIPK2 recruits SRSF1 to increase TXNIP mRNA stability and promotes autophagy-dependent ferroptosis and apoptosis in myocardial ischemia-reperfusion injury
Our results demonstrate that circHIPK2 contributes to MIRI through inducing oxidative stress and autophagy-dependent ferroptosis via SRSF1/TXNIP axis, offering new insights into MIRI treatment.
Authors
- Yan‐Qin Yu (ORCID: https://orcid.org/0000-0002-4378-5931)
- Qiyun Qiao (ORCID: https://orcid.org/0000-0003-4848-553X)
- Jinqi Hao
- Zhu Zhang (ORCID: https://orcid.org/0000-0002-0635-8260)
- Junting Song
Institutions
- Baotou Medical College (CN)
Publication Details
- Journal
- Journal of Cardiothoracic Surgery
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1186/s13019-024-03325-2
- Citations
- 3
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Natural Science Foundation of Inner Mongolia