Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells
HPE improves serum ALT levels via anti-inflammatory mechanisms in macrophages and senescent cells. HPE serves as a novel agent for cirrhosis treatment.
Authors
- Hiroyuki Abé (ORCID: https://orcid.org/0000-0003-2618-7494)
- Shuji Terai (ORCID: https://orcid.org/0000-0002-5439-635X)
- Yoshinobu Maeda (ORCID: https://orcid.org/0000-0003-1634-5487)
- Yusuke Watanabe (ORCID: https://orcid.org/0000-0001-7869-0409)
- Naruhiro Kimura (ORCID: https://orcid.org/0000-0001-6683-1219)
- Natsuki Ishikawa
- Akira Sakamaki (ORCID: https://orcid.org/0000-0002-9368-7272)
- Atsunori Tsuchiya (ORCID: https://orcid.org/0000-0002-9279-5917)
- Takeshi Yokoo (ORCID: https://orcid.org/0000-0001-7138-1785)
- Tomoaki Yoshida (ORCID: https://orcid.org/0000-0001-6544-2473)
- Hiroteru Kamimura (ORCID: https://orcid.org/0000-0002-9135-3092)
- Kenya Kamimura (ORCID: https://orcid.org/0000-0001-7182-4400)
Institutions
- Niigata University (JP)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1016/j.reth.2025.01.017
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Japan Society for the Promotion of Science