Detection of <i>Chlamydia trachomatis ompA</i> DNA in urine by loop-mediated isothermal amplification (LAMP) assay
The LAMP-SYBR GOLD assay showed a sensitivity of 71 % and a high specificity for detecting CT in urine with extraction method-1. The use of method-2 could increase this sensitivity, likely due to the removal of urine inhibitors.
Authors
- Nalaka Abeygunasekera
- Charitha L. Goonasekara (ORCID: https://orcid.org/0000-0002-6956-0095)
- Kamani Mangalika Gunasekera (ORCID: https://orcid.org/0000-0002-1132-5121)
- Jayanthi Elvitigala
- Hemali Attanayake
Institutions
- University of Sri Jayewardenepura (LK)
- General Sir John Kotelawala Defence University (LK)
- Colombo North Teaching Hospital (LK)
Publication Details
- Journal
- Advances in Laboratory Medicine / Avances en Medicina de Laboratorio
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1515/almed-2024-0117
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chulalongkorn University
- University of Sri Jayewardenepura
- Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu
- Statens Serum Institut
- Faculty of Science, Chulalongkorn University