LPA released from dying cancer cells after chemotherapy inactivates Hippo signaling and promotes pancreatic cancer cell repopulation
Our investigation indicated that targeting the LPA-YAP1 signaling pathway could serve as a promising strategy to augment the overall therapeutic efficacy against PDAC.
Authors
- Ming Quan (ORCID: https://orcid.org/0000-0002-0828-1324)
- Shumin Li (ORCID: https://orcid.org/0000-0001-8083-1071)
- Jie Ding (ORCID: https://orcid.org/0000-0002-1427-9618)
- Yuzhi Liu (ORCID: https://orcid.org/0000-0002-4642-2925)
- Zhiqin Chen
- Anyi Jiang
Institutions
- Tongji University (CN)
- Renji Hospital (CN)
- Shanghai Cancer Institute (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- Cellular Oncology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1007/s13402-025-01038-9
- Citations
- 1
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China