Spontaneous Pain and Pain Sensitivity in Response to Prolonged Experimental Sleep Disturbances—Potential Sex Differences
Exploration of sex as a modulator suggest that sleep disturbances amplify spontaneous pain and pressure pain sensitivity to a greater extent in females than in males, and this may contribute to females' overrepresentation and disproportionate symptom burden observed for many pain-related disorders for which insomnia is comorbid or a risk factor.
Authors
- Navil F. Sethna (ORCID: https://orcid.org/0000-0003-2200-9826)
- Suzanne M. Bertisch (ORCID: https://orcid.org/0000-0002-4627-8871)
- Michael R. Goldstein (ORCID: https://orcid.org/0000-0002-1460-8012)
- Larissa C. Engert (ORCID: https://orcid.org/0000-0001-8912-2271)
- Luciana Besedovsky (ORCID: https://orcid.org/0000-0001-6053-3245)
- Monika Haack (ORCID: https://orcid.org/0000-0001-6214-4294)
- Rammy Dang (ORCID: https://orcid.org/0000-0003-4014-6429)
- Keeyon Olia (ORCID: https://orcid.org/0000-0002-7104-4241)
Institutions
- Brigham and Women's Hospital (US)
- Boston Children's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Circadian (United States) (US)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1002/ejp.4789
- Citations
- 3
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 4.41