Folic acid versus folinic acid during methotrexate treatment for low-risk gestational trophoblastic neoplasia

Replacement of folinic acid with folic acid in low-risk GTN patients to reduce the toxicity that may develop associated with MTX treatment resulted in similar treatment success rates. Still, no significant change was observed regarding toxicity and resistance. There is a need for comprehensive prospective studies to further elucidate this relationship.

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Publication Details

Journal
Ginekologia Polska
Published
2025-02-04
DOI
https://doi.org/10.5603/gpl.101142
Citations
1
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
Field-Weighted Citation Impact
1.88
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article

Folic acid versus folinic acid during methotrexate treatment for low-risk gestational trophoblastic neoplasia

Gökhan Bolluk, Sedat Akgöl, Behzat Can, Adnan Budak et al.
1 citations
Ginekologia Polska
Gestational Trophoblastic Disease Studies
1.88
article

Folic acid versus folinic acid during methotrexate treatment for low-risk gestational trophoblastic neoplasia

Gökhan Bolluk, Sedat Akgöl, Behzat Can, Adnan Budak, Özgür Akbayır, Emine Zeynep Yılmaz, Şeyhmus Tunç, Süleyman Cemil Oğlak, Mehmet Şükrü Budak, Mesut Ali Halisçelik, Kevser Arkan, Ali Deniz Erkmen
article en
1 citations

Abstract

Replacement of folinic acid with folic acid in low-risk GTN patients to reduce the toxicity that may develop associated with MTX treatment resulted in similar treatment success rates. Still, no significant change was observed regarding toxicity and resistance. There is a need for comprehensive prospective studies to further elucidate this relationship.

Ginekologia PolskaVol. 96(3)
Istanbul Metropolitan Municipality (TR), Memorial Sisli Hospital (TR), Sağlık Bilimleri Üniversitesi (TR), Universidad CES (CO), Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi (TR)
Zero hunger
Openalex Percentile: Top 19%
Gestational Trophoblastic Disease Studies
1.88
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Folic acid versus folinic acid during methotrexate treatment for low-risk gestational trophoblastic neoplasia — Gökhan Bolluk, Sedat Akgöl, et al. · Ginekologia Polska (2025) | TGRS Research Map | TGRS