Metabolic and Hepatic Profiles of Non-Obese and Obese Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents: The Role of FibroScan Parameters,Fibroblast Growth Factor-21, and Cytokeratin-18
Fibroblast growth factor-21 has emerged as a potential biomarker for assessing metabolic dysfunction in MASLD, while LSMs from FibroScan provide valuable insights into fibrosis risk. Elevated FGF-21 levels and FibroScan parameters reflect their potential usefulness in non-invasive assessment of MASLD severity, particularly in obese adolescents. However, further longitudinal studies are needed to establish their roles in predicting disease progression and guiding clinical management.
Authors
- Nizameddin Koca (ORCID: https://orcid.org/0000-0003-1457-4366)
- Murat Keskın (ORCID: https://orcid.org/0000-0003-4526-4352)
- Emre Sarandöl (ORCID: https://orcid.org/0000-0002-2593-7196)
- Hanife Ayşegül Arsoy (ORCID: https://orcid.org/0000-0002-3970-0894)
- Özlem Kara (ORCID: https://orcid.org/0000-0003-0915-5546)
- Yusuf Nadir Yilmaz (ORCID: https://orcid.org/0000-0003-4518-5283)
- Aylin Beyaz (ORCID: https://orcid.org/0000-0002-8053-8016)
Institutions
- Bursa Uludağ Üni̇versi̇tesi̇ (TR)
- Recep Tayyip Erdoğan University (TR)
- Bursa Technical University (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- KTO Karatay University (TR)
- S.B.Ü. Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi (TR)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2025-02-03
- DOI
- https://doi.org/10.5152/tjg.2025.24760
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71