Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol

The treatment of unfavorable nonfunctioning pituitary macroadenoma with 5-fraction robotic radiosurgery provides excellent local control to date, with acceptable toxicity. However, tumors with GTVs greater than 20 cc may still require conventionally fractionated treatment with a margin to optimize local control.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-02-04
DOI
https://doi.org/10.3389/fonc.2025.1519445
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
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article

Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol

Siviero Agazzi, Walter C. Jean, Akrita Bhatnagar, Brent T. Harris et al.
Frontiers in Oncology
Pituitary Gland Disorders and Treatments
article

Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol

Siviero Agazzi, Walter C. Jean, Akrita Bhatnagar, Brent T. Harris, Edward F. Aulisi, Simeng Suy, Susmeeta T. Sharma, Min Ji Koh, Jonathan W. Lischalk, Mohamed H. Khattab, Monica Pernia Marin, Sean P. Collins, Amjad Anaizi, Brian T. Collins
article en

Abstract

The treatment of unfavorable nonfunctioning pituitary macroadenoma with 5-fraction robotic radiosurgery provides excellent local control to date, with acceptable toxicity. However, tumors with GTVs greater than 20 cc may still require conventionally fractionated treatment with a margin to optimize local control.

Frontiers in OncologyVol. 15
MedStar Washington Hospital Center (US), Lehigh Valley Hospital-Pocono (US), Georgetown University (US), University of South Florida (US), Columbia University Irving Medical Center (US), NYU Langone Health (US)
Good health and well-being
Openalex Percentile: Top 97%
Pituitary Gland Disorders and Treatments
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