Association of pituitary neuroendocrine tumors and neurofibromatosis type 1: assessing causation versus coincidence. Case report
Although the association of NF1 and PitNETs could be coincidental, the clinical characteristics of the reviewed cases differ from those of typical incidentalomas. <i>NF1</i> could drive pituitary tumorigenesis via haploinsufficiency, but this hypothesis requires further research. Additional clinical and molecular data from large cohorts of affected individuals should help clarify this question.
Authors
- Armando Gamboa‐Domínguez (ORCID: https://orcid.org/0000-0002-1983-0384)
- Julia M. Zuarth-Vázquez (ORCID: https://orcid.org/0000-0001-7872-7160)
- Aldo Eguiluz‐Melendez (ORCID: https://orcid.org/0000-0002-7083-4612)
- Karla Zarco-Ávila (ORCID: https://orcid.org/0000-0002-1530-0976)
- Laura C. Hernández‐Ramírez (ORCID: https://orcid.org/0000-0002-6599-6406)
- Mercedes Aguilar-Soto (ORCID: https://orcid.org/0000-0002-3522-8406)
- Laura Leyva-Figueroa
Institutions
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.3389/fendo.2025.1483305
- Citations
- 1
- Primary Topic
- Neurofibromatosis and Schwannoma Cases
- Type
- article
- Field-Weighted Citation Impact
- 1.39