Hypereosinophilic Syndrome in a Patient With Complex Pulmonary Hypertension and Sjogren’s Syndrome: A Case Report

We describe the case of a 73-year-old man who had been followed up by our clinic for pulmonary hypertension and asthma. He was later hospitalized and found to have significant and persistent eosinophilia compatible with hypereosinophilic syndrome. Various other conditions such as drug reaction with eosinophilia and systemic symptoms (DRESS), malignancy, and eosinophilic granulomatosis with polyangiitis (EGPA) were considered but largely excluded after further investigation. He responded well to steroids and was transitioned to mepolizumab for long-term control.