To evaluate the Clinical Efficacy of the Cocktail and 15% hypertonic Dextrose Solution Injection for Plantar Fasciitis

Background: Plantar fasciitis as a cause of heel pain results from the degeneration of the plantar fascia.Risk factors include obesity, shorting of the Achilles tendons, and letting weight-bearing activities continue for long periods.Diagnosis is done through physical examinations and ultrasonographic evaluations.Management options are non-surgical treatments like shockwave therapy, exercise-based adaptive changes, and tissue regenerative therapies like hypertonic dextrose stimulation.The aim of this study compare the clinical efficiency of cocktail therapy versus 15% hypertonic dextrose explanation injections for plantar fasciitis treatment.Methods: This randomized clinical trial was conducted from November 2023 to October 2024 and included 41 participants aged 20-70 years, suffering from heel pain for >4 months.The pain was assessed using the visual analogue scale (VAS) and the American Orthopaedic Foot and Ankle Society (AOFAS) scales.Under ultrasound guidance, participants were assigned either cocktail (methylprednisolone, lignocaine) or hypertonic dextrose injection treatments, followed by pain and functional improvement assessment at 1-, 3-, and 6-months post-injection.Results: Prolotherapy and cocktail treatments were compared in the study conducted for patients suffering from plantar fasciitis.Both groups have nearly the same demographics and baseline characteristics.Although both improved, the past six months had the cocktail group with more VAS and AOFAS.The ultrasound-guided injections assured the precise delivery of treatment, improving the efficacy by targeting the inflamed plantar fascia correctly. Conclusion:This study concluded that both prolotherapy and cocktail treatments are effective for plantar fasciitis, with cocktail treatment yielding superior pain reduction and functional development.Ultrasound-guided injections confirmed accurate, targeted delivery.