Freiburg index of post-TIPS survival (FIPS) identifies patients at risk of further decompensation and ACLF after TIPS
Prognostication after transjugular intrahepatic portosystemic shunt (TIPS) implantation is challenging. Several clinical scores have been proposed in this context, such as the Freiburg index of post-TIPS survival (FIPS). The FIPS can identify a high-risk group of patients with significantly reduced survival after TIPS. However, to understand the reasons for these patients' unfavorable outcome, their clinical course after TIPS needs to be characterized. This study reveals that the FIPS predicts development of further decompensation and acute-on-chronic liver failure after TIPS implantation, which are responsible for the poor prognosis of FIPS high-risk patients. Therefore, the present results may be useful for tailored decision making in patients allocated to TIPS implantation.
Authors
- Anja Tiede (ORCID: https://orcid.org/0000-0002-5936-8307)
- Michael Schultheiß (ORCID: https://orcid.org/0000-0001-8000-1721)
- Fabian Stöhr
- Felix Piecha (ORCID: https://orcid.org/0000-0002-2781-5088)
- Markus Kimmann
- Christian Labenz (ORCID: https://orcid.org/0000-0001-8390-9663)
- Tony Bruns (ORCID: https://orcid.org/0000-0002-5576-6914)
- Maike R. Pollmanns
- Charlotte Rohrer
- Jonel Trebicka (ORCID: https://orcid.org/0000-0002-7028-3881)
- Alexander Zipprich (ORCID: https://orcid.org/0000-0001-8403-7983)
- Benjamin Maasoumy (ORCID: https://orcid.org/0000-0002-3250-3177)
- Dominik Bettinger (ORCID: https://orcid.org/0000-0002-8782-8729)
- Cristina Ripoll (ORCID: https://orcid.org/0000-0002-9704-4741)
- Robert Thimme (ORCID: https://orcid.org/0000-0003-1417-4135)
- Michael Praktiknjo (ORCID: https://orcid.org/0000-0001-7033-9956)
- Jakub Grobelski (ORCID: https://orcid.org/0000-0003-4066-3469)
- Marlene Reincke (ORCID: https://orcid.org/0009-0008-2911-4163)
- Christian Jansen (ORCID: https://orcid.org/0000-0003-4475-9644)
- Johannes Kluwe (ORCID: https://orcid.org/0000-0002-7302-5511)
- Leon Louis Seifert (ORCID: https://orcid.org/0000-0002-0089-7669)
- Saman Arbabi (ORCID: https://orcid.org/0000-0002-1006-9664)
- Uli Fehrenbach (ORCID: https://orcid.org/0000-0003-3622-3268)
- Jan B. Hinrichs (ORCID: https://orcid.org/0000-0002-0135-7082)
- Lukas Sturm (ORCID: https://orcid.org/0000-0002-3623-7857)
- Roman Kloeckner (ORCID: https://orcid.org/0000-0001-5492-4792)
- Aenne Harberts (ORCID: https://orcid.org/0000-0002-0143-8106)
- Johannes Chang (ORCID: https://orcid.org/0000-0001-9635-8901)
- Timo Alexander Auer (ORCID: https://orcid.org/0000-0002-5763-689X)
- Michael Koehler
- Carsten H. Meyer
Institutions
- Universität Hamburg (DE)
- University of Freiburg (DE)
- Johannes Gutenberg University Mainz (DE)
- University Hospital Bonn (DE)
- University Medical Center Freiburg (DE)
- Medizinische Hochschule Hannover (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- University Hospital Münster (DE)
- St. Bernward Krankenhaus (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Jena University Hospital (DE)
- Friedrich Schiller University Jena (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Rockefeller University (US)
- RWTH Aachen University (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Journal of Hepatology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1016/j.jhep.2025.01.030
- Citations
- 10
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 13.22