Aberrant Functional Connectivity and Brain Network Organization in High-Schizotypy Individuals: An Electroencephalography Study
These results show that healthy individuals with a higher risk of developing psychosis exhibit a less efficient functional brain organization, coupled with a systematic decrease in functional connectivity impacting both bottom-up and top-down processing. These frequency-specific network alterations provide robust support for the dimensional model of schizophrenia, highlighting distinctive neurophysiological signatures in high-schizotypy individuals.
Authors
- Elisa Magosso (ORCID: https://orcid.org/0000-0002-4673-2974)
- Vincenzo Romei (ORCID: https://orcid.org/0000-0003-1214-2316)
- Luca Tarasi (ORCID: https://orcid.org/0000-0002-4977-3173)
- Gabriele Pirazzini (ORCID: https://orcid.org/0009-0008-7858-9317)
- Giulia Ricci (ORCID: https://orcid.org/0000-0001-5248-1625)
- Mauro Ursino (ORCID: https://orcid.org/0000-0002-0911-0308)
- Jelena Trajkovic (ORCID: https://orcid.org/0000-0002-1215-2410)
- Francesco Di Gregorio (ORCID: https://orcid.org/0000-0002-3587-3149)
Institutions
- Netherlands Institute for Neuroscience (NL)
- Royal Netherlands Academy of Arts and Sciences (NL)
- Universidad Nebrija (ES)
- Maastricht University (NL)
- University of Bologna (IT)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1093/schbul/sbaf004
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Ministerio de Ciencia, Innovación y Universidades
- Fundação Bial
- Ministero dell'Università e della Ricerca