Radical 1,3-Hydrosulfonylation of Vinyldiazo Compounds with Sulfinyl Sulfones
Sulfinyl sulfones, as high-valence sulfurization reagents, are widely used to assemble sulfur sources on carbon skeletons, such as one-, two-, and four-carbon synthons, to access organosulfur compounds. However, their reaction with three-carbon synthons has remained a mystery until now. We report here a radical 1,3-hydrosulfonylation of vinyldiazo compounds with sulfinyl sulfones. This reaction not only represents the first example of the reaction of sulfinyl sulfones with three-carbon synthons but also opens up the application of vinyldiazo compounds in radical monofunctionalization.
Authors
- Zikun Wang (ORCID: https://orcid.org/0000-0002-8672-4311)
- Yuan‐Li Ding (ORCID: https://orcid.org/0000-0002-3217-8183)
- Tian Jing (ORCID: https://orcid.org/0000-0001-9916-650X)
- Zixu Zhang (ORCID: https://orcid.org/0000-0002-5759-8715)
- Wanting Fu
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Yanbian University (CN)
- Hebei University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1021/acs.orglett.4c04652
- Citations
- 6
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 5.62
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hebei Province
- Hebei University
- Hebei Provincial Department of Bureau of Science and Technology
- Jilin Scientific and Technological Development Program