Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development
In two independent in vitro screening approaches against two stages of S. mansoni one common interesting structure with rapid effects was identified, OGHL00022, which provides opportunities for further development.
Authors
- Cécile Häberli (ORCID: https://orcid.org/0000-0002-1282-8070)
- Christoph Gero Grevelding (ORCID: https://orcid.org/0000-0002-3144-2026)
- Monique Evelyn Ueberall
- Thomas Spangenberg (ORCID: https://orcid.org/0000-0002-5654-8919)
- Jennifer Keiser
- Martina Berchthold
- Sven Lindemann
Institutions
- Swiss Tropical and Public Health Institute (CH)
- Merck KGaA, Darmstadt (Germany) (DE)
- University of Basel (CH)
- Justus-Liebig-Universität Gießen (DE)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1186/s13071-024-06648-0
- Citations
- 3
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 6.14
Funders
- Deutsche Forschungsgemeinschaft