Rest-Activity Rhythms, Their Modulators, and Brain-Clinical Correlates in Opioid Use Disorder
Findings of this cross-sectional study showed that sleep irregularity in participants with OUD receiving opioid agonist medications correlated with years of opioid misuse and shorter daylight exposures and was associated with impaired brain state dynamics. These findings suggest that interventions increasing light exposure may improve sleep-wake irregularity and brain functional network dynamics in individuals with OUD receiving opioid agonist medications.
Authors
- Michele-Vera Yonga
- Ehsan Shokri‐Kojori (ORCID: https://orcid.org/0000-0001-6846-3173)
- Şükrü Barış Demiral (ORCID: https://orcid.org/0000-0002-5288-603X)
- Dardo G. Tomasi (ORCID: https://orcid.org/0000-0003-0183-5678)
- Peter Manza (ORCID: https://orcid.org/0000-0002-0791-357X)
- Natasha T. Giddens (ORCID: https://orcid.org/0000-0003-0368-1780)
- Weizheng Yan (ORCID: https://orcid.org/0000-0002-0885-5631)
- Melanie L. Schwandt (ORCID: https://orcid.org/0000-0002-8355-4900)
- Diana Sotelo (ORCID: https://orcid.org/0000-0002-5152-9882)
- Leah Vines
- Christina Lildharrie
- Rui Zhang (ORCID: https://orcid.org/0000-0002-7481-0917)
- Esther Lin
- Gene Jack Wang
- Nora D. Volkow
Institutions
- National Institutes of Health (US)
- University of Wisconsin–Madison (US)
- National Institute on Alcohol Abuse and Alcoholism (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.57976
- Citations
- 6
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 12.71