A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer
In conclusion, the HTTR signature served as a robust prognostic biomarker for GC patients and effectively identified those with immune "hot" tumors. This finding provided valuable insights into the molecular mechanisms of tumor immunity in GC, offering potential avenues for targeted therapeutic interventions.
Authors
- Hong Zhou (ORCID: https://orcid.org/0000-0003-0120-3347)
- Yuqiang Shan
- Chenxi Lv
- Jiangtao Li (ORCID: https://orcid.org/0000-0001-7538-2910)
- Tianwei Chen (ORCID: https://orcid.org/0009-0006-1292-0826)
Institutions
- Wenzhou Medical University (CN)
- Westlake University (CN)
- Wenzhou Central Hospital (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1007/s00262-025-03954-z
- Citations
- 5
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 3.75