Randomized controlled trial of 4.0 mg versus 0.4 mg folic acid supplementation: Follow-up of children at 1 year of age
The findings suggest that the periconception FA supplementation of 4.0 mg/day versus 0.4 mg/day, does not affect the health status and hospitalizations from birth to 1 year of life, as well as normal child's developmental milestones at 1 year of life. The increase in exclusive breastfeeding in the 4.0 mg FA group needs further investigation.
Authors
- Fabio Parazzini (ORCID: https://orcid.org/0000-0001-5624-4854)
- Federico Marchetti (ORCID: https://orcid.org/0000-0002-1257-7312)
- Francesca Filippini (ORCID: https://orcid.org/0000-0001-5884-8635)
- Daniele Trevisanuto (ORCID: https://orcid.org/0000-0002-6462-0079)
- Francesco Cavallin (ORCID: https://orcid.org/0000-0002-0831-3971)
- Sonia Cipriani (ORCID: https://orcid.org/0000-0002-0530-499X)
- Pierpaolo Mastroiacovo (ORCID: https://orcid.org/0000-0002-8318-8664)
- Renata Bortolus (ORCID: https://orcid.org/0000-0003-3857-4133)
Institutions
- University of Verona (IT)
- University of Padua (IT)
- University of Milan (IT)
- BirdLife International (KE)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale "Santa Maria delle Croci" di Ravenna (IT)
- Statisticon (Sweden) (SE)
Publication Details
- Journal
- European Journal of Obstetrics & Gynecology and Reproductive Biology X
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1016/j.eurox.2025.100370
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agenzia Italiana del Farmaco, Ministero della Salute