Differentiating Contact with Symptomatic and Asymptomatic Infectious Individuals in a SEIR Epidemic Model

This manuscript introduces a new Erlang-distributed SEIR model. The model incorporates asymptomatic spread through a subdivided exposed class, distinguishing between asymptomatic ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mtext>E</mml:mtext> <mml:mi>a</mml:mi></mml:msub> </mml:math> ) and symptomatic ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mtext>E</mml:mtext> <mml:mi>s</mml:mi></mml:msub> </mml:math> ) cases. The model identifies two key parameters: relative infectiousness, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>β</mml:mi> <mml:mrow><mml:mi>SA</mml:mi></mml:mrow> </mml:msub> </mml:math> , and the percentage of people who become asymptomatic after being infected by a symptomatic individual, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>κ</mml:mi></mml:math> . Lower values of these parameters reduce the peak magnitude and duration of the infectious period, highlighting the importance of isolation measures. Additionally, the model underscores the need for strategies addressing both symptomatic and asymptomatic transmissions.

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Publication Details

Journal
Bulletin of Mathematical Biology
Published
2025-02-04
DOI
https://doi.org/10.1007/s11538-025-01416-2
Citations
6
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
8.21

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article

Differentiating Contact with Symptomatic and Asymptomatic Infectious Individuals in a SEIR Epidemic Model

Victoria Chebotaeva, Aswin Srinivasan, Paula A. Vásquez
6 citations
Bulletin of Mathematical Biology
COVID-19 epidemiological studies
8.21
article

Differentiating Contact with Symptomatic and Asymptomatic Infectious Individuals in a SEIR Epidemic Model

Victoria Chebotaeva, Aswin Srinivasan, Paula A. Vásquez
article en
6 citations

Abstract

This manuscript introduces a new Erlang-distributed SEIR model. The model incorporates asymptomatic spread through a subdivided exposed class, distinguishing between asymptomatic ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mtext>E</mml:mtext> <mml:mi>a</mml:mi></mml:msub> </mml:math> ) and symptomatic ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mtext>E</mml:mtext> <mml:mi>s</mml:mi></mml:msub> </mml:math> ) cases. The model identifies two key parameters: relative infectiousness, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>β</mml:mi> <mml:mrow><mml:mi>SA</mml:mi></mml:mrow> </mml:msub> </mml:math> , and the percentage of people who become asymptomatic after being infected by a symptomatic individual, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mi>κ</mml:mi></mml:math> . Lower values of these parameters reduce the peak magnitude and duration of the infectious period, highlighting the importance of isolation measures. Additionally, the model underscores the need for strategies addressing both symptomatic and asymptomatic transmissions.

Bulletin of Mathematical BiologyVol. 87(3)
University of South Carolina (US)
National Science Foundation, University of South Carolina
Good health and well-being
Openalex Percentile: Top 2%
COVID-19 epidemiological studies
8.21
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