ESPGHAN and NASPGHAN 2024 protocol for paediatric functional constipation treatment guidelines (standard operating procedure)
'Grading of Recommendations Assessment, Development and Evaluation' (GRADE) will be used for all phases of this guideline development. The Guideline Development Group is formed by paediatric gastroenterologists from both the ESPGHAN as well as the NASPGHAN. A prospective exercise will agree on key outcomes, thresholds of magnitude that are significant at small, moderate and large levels. Systematic evidence searches, selection, extraction, appraisal and analysis will be performed following Cochrane guidance and GRADE guidance for objectively agreeing the certainty of findings. Additional use of network meta-analysis will identify areas of broad triangulation in the evidence. Summary of findings tables will be produced and inform evidence to decision frameworks. These will guide GRADE recommendations with voting to reach a consensus.
Authors
- Samuel Nurko (ORCID: https://orcid.org/0000-0003-0936-4807)
- Nikhil Thapar (ORCID: https://orcid.org/0000-0002-0276-9951)
- Dawn Dore‐Stites (ORCID: https://orcid.org/0000-0002-1240-4358)
- Morris A. Gordon (ORCID: https://orcid.org/0000-0002-1216-5158)
- Anna de Geus (ORCID: https://orcid.org/0000-0002-2282-0128)
- Merit Monique Tabbers (ORCID: https://orcid.org/0000-0001-9744-7308)
- Mary Boruta
- Alexandra Kilgore (ORCID: https://orcid.org/0000-0001-8139-0351)
- Michelle Gould (ORCID: https://orcid.org/0000-0002-4204-922X)
- Anil Darbari (ORCID: https://orcid.org/0000-0002-3088-9539)
- Julie Khlevner (ORCID: https://orcid.org/0000-0001-8166-0382)
- Osvaldo Borrelli
- Vassiliki Sinopoulou (ORCID: https://orcid.org/0000-0002-2831-9406)
- Hayat Mousa (ORCID: https://orcid.org/0000-0002-2858-8171)
- Marcin Banasiuk (ORCID: https://orcid.org/0000-0003-1713-7372)
- Juliette T. Hawa
- Marc Alexander Benninga (ORCID: https://orcid.org/0000-0001-9406-9188)
- K Jones
Institutions
- Boston Children's Hospital (US)
- Morgan Stanley Children's Hospital (US)
- Nationwide Children's Hospital (US)
- Children's Hospital of Philadelphia (US)
- Children's National (US)
- Duke University (US)
- University of Lancashire (GB)
- Medical University of Warsaw (PL)
- Great Ormond Street Hospital (GB)
- Hospital for Sick Children (CA)
- Children's Hospital Colorado (US)
- Emma Kinderziekenhuis (NL)
- Michigan Medicine (US)
- Amsterdam University Medical Centers (NL)
- Children's Health Queensland Hospital and Health Service (AU)
- University College London (GB)
- University of Amsterdam (NL)
- University of Colorado Denver (US)
Publication Details
- Journal
- BMJ Paediatrics Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/bmjpo-2024-003161
- Citations
- 10
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 18.11
Funders
- North American Society for Pediatric Gastroenterology, Hepatology and Nutrition