Revealing the limitations of 10-year MACE observations: 20-year observed total cardiovascular burden in the EPIC-Norfolk study
The observed incidence of CVD roughly triples from 10 to 20 years of follow-up, with 10-year MACE observations underestimating 20-year total CVD burden by a factor ranging from 3 (older men) to 10 (younger women). These findings highlight the limitations of communicating 10-year MACE risk assessments to facilitate informed decisions in longer-term CVD prevention-particularly in younger women.
Authors
- H T Jørstad (ORCID: https://orcid.org/0000-0003-3617-3256)
- Ron J.G. Peters (ORCID: https://orcid.org/0000-0002-3642-5022)
- Maud van den Bogaart (ORCID: https://orcid.org/0000-0003-2159-6942)
- T J Van Trier (ORCID: https://orcid.org/0000-0002-2956-8121)
- Marjolein Snaterse (ORCID: https://orcid.org/0000-0002-4923-6845)
- Jannick A N Dorresteijn (ORCID: https://orcid.org/0000-0002-0190-8526)
- Frank L.J. Visseren (ORCID: https://orcid.org/0000-0003-3951-5223)
- S. Matthijs Boekholdt (ORCID: https://orcid.org/0000-0002-0861-0765)
- Wilma JM Scholte op Reimer
Institutions
- University of Applied Sciences Utrecht (NL)
- Utrecht University (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Open Heart
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/openhrt-2024-002981
- Citations
- 1
- Primary Topic
- Health Promotion and Cardiovascular Prevention
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Cancer Research UK
- Medical Research Council