The prevalence and clinical significance of residual occult breast cancer after neoadjuvant chemotherapy: reassessing surgical pathology in cases initially described as pathological complete response
In patients with TNBC and HER2+ breast cancer with pCR by standard pathological assessment, occult residual disease is not uncommon. Occult disease was not associated with worse oncological or survival outcomes, suggesting standard pathological assessment is sufficient to identify clinically meaningful disease.
Authors
- Eliel N. Arrey
- Lauren M. Postlewait
- Di Ai (ORCID: https://orcid.org/0000-0003-2972-4582)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-6365-7646)
- Xiaoxian Li (ORCID: https://orcid.org/0000-0002-0995-1721)
Institutions
- Grady Memorial Hospital (US)
- Emory University (US)
- Morehouse School of Medicine (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Histopathology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1111/his.15417
- Citations
- 2
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.87