Liver metastases do not predict resistance to the addition of atezolizumab to first-line FOLFOXIRI plus bevacizumab in proficient MMR metastatic colorectal cancer: a secondary analysis of the AtezoTRIBE study
LMs are associated with poor prognosis in pMMR mCRC and do not predict resistance to the addition of atezolizumab to FOLFOXIRI/bevacizumab. Immunoscore-IC seems to retain its predictive impact also among patients with LMs.
Authors
- Veronica Conca (ORCID: https://orcid.org/0000-0001-7713-4005)
- Clara Ugolini (ORCID: https://orcid.org/0000-0002-3489-8280)
- Maria Alessandra Calegari (ORCID: https://orcid.org/0000-0001-6856-2593)
- Emiliano Tamburini (ORCID: https://orcid.org/0000-0003-4619-7091)
- Lisa Salvatore (ORCID: https://orcid.org/0000-0003-3864-0719)
- C. Antoniotti
- G. Aprile (ORCID: https://orcid.org/0000-0003-2634-1607)
- Caterina Sciortino (ORCID: https://orcid.org/0000-0002-9703-8392)
- S. Tamberi
- Sara Lonardi (ORCID: https://orcid.org/0000-0002-7593-8138)
- F. Bergamo
- P. Ciracì
- Jérôme Galon (ORCID: https://orcid.org/0000-0001-9635-1339)
- Martina Carullo (ORCID: https://orcid.org/0000-0003-2846-2517)
- Daniele Rossini (ORCID: https://orcid.org/0009-0000-3777-8471)
- Giuliana Ritorto
- Carla Boccaccio (ORCID: https://orcid.org/0000-0003-2620-9083)
- Chiara Cremolini (ORCID: https://orcid.org/0000-0002-0520-4841)
- F. Pietrantonio
- Alessandro Passardi (ORCID: https://orcid.org/0000-0002-7099-240X)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Pisa (IT)
- Inserm (FR)
- Université Paris Cité (FR)
- Agostino Gemelli University Polyclinic (IT)
- Sorbonne Université (FR)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Centre de Recherche des Cordeliers (FR)
- Ospedale "Santa Maria delle Croci" di Ravenna (IT)
- Ospedale di Cattinara (IT)
- Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IT)
- Istituto Oncologico Veneto (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Laboratoire d’immunologie intégrative du cancer (FR)
- Ospedale San Bortolo (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
- University of Florence (IT)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.esmoop.2025.104135
- Citations
- 6
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.23
Funders
- Università di Pisa