Intraepithelial corneal deposits associated with Mirvetuximab soravtansine use for platinum-resistant ovarian cancer

The natural reversibility of MIRV-induced keratopathies underscores the need for prompt and regular ophthalmic assessments throughout drug administration. Understanding the mechanism behind these corneal changes, how to recognize them in a clinical setting, and expedite their reversal are essential to improve quality-of-life metrics in patients receiving MIRV transfusions.

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Publication Details

Journal
American Journal of Ophthalmology Case Reports
Published
2025-02-05
DOI
https://doi.org/10.1016/j.ajoc.2025.102271
Citations
1
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
1.70
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article

Intraepithelial corneal deposits associated with Mirvetuximab soravtansine use for platinum-resistant ovarian cancer

Charlotte McRae, Jack S. Parker, M. I. Green, Richard Cowan
1 citations
American Journal of Ophthalmology Case Reports
Ovarian cancer diagnosis and treatment
1.70
article

Intraepithelial corneal deposits associated with Mirvetuximab soravtansine use for platinum-resistant ovarian cancer

Charlotte McRae, Jack S. Parker, M. I. Green, Richard Cowan
article en
1 citations

Abstract

The natural reversibility of MIRV-induced keratopathies underscores the need for prompt and regular ophthalmic assessments throughout drug administration. Understanding the mechanism behind these corneal changes, how to recognize them in a clinical setting, and expedite their reversal are essential to improve quality-of-life metrics in patients receiving MIRV transfusions.

American Journal of Ophthalmology Case ReportsVol. 38
University of Alabama at Birmingham (US), Vesta Sciences (United States) (US)
Zero hunger
Openalex Percentile: Top 20%
Ovarian cancer diagnosis and treatment
1.70
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