Associations between decreases in adiposity and reductions in <scp>HbA1c</scp> and insulin use in the Look <scp>AHEAD</scp> cohort
Reductions in adiposity are associated with stabilized and slightly lower HbA1c and a marked reduction in the need for insulin therapy. These benefits generalize across clinical subgroups.
Authors
- Karen Johnson (ORCID: https://orcid.org/0000-0002-3493-4077)
- Kristen M. Beavers (ORCID: https://orcid.org/0000-0002-7786-4195)
- Rebecca H. Neiberg (ORCID: https://orcid.org/0000-0003-0719-6520)
- Rebecca Palmer (ORCID: https://orcid.org/0009-0004-2030-7031)
- Denise K. Houston (ORCID: https://orcid.org/0000-0002-3355-4304)
- Steven E. Kahn (ORCID: https://orcid.org/0000-0001-7307-9002)
- Mark A. Espeland (ORCID: https://orcid.org/0000-0002-3711-1949)
- Lynne E. Wagenknecht (ORCID: https://orcid.org/0000-0002-9980-0889)
- Henry J. Pownall (ORCID: https://orcid.org/0000-0001-8412-506X)
Institutions
- University of Tennessee Health Science Center (US)
- University of Washington (US)
- Cornell University (US)
- VA Puget Sound Health Care System (US)
- Wake Forest University (US)
Publication Details
- Journal
- Obesity
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1002/oby.24242
- Citations
- 4
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 5.18
Funders
- U.S. Department of Veterans Affairs
- Dairy Management
- University of Pittsburgh
- Deutsches Krebsforschungszentrum
- National Institutes of Health
- Centers for Disease Control and Prevention
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute of Nursing Research
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Center on Minority Health and Health Disparities
- Office of Research on Women's Health
- National Institute on Minority Health and Health Disparities