Decoding mutational signatures in breast cancer: Insights from a multi-cohort study
The use of comprehensive genomic profiling provided accurate evaluation of the TMB and extraction of signatures consistent with published literature. The genomic analysis of the tissue samples of the CICLADES cohort brings new and relevant data, comparable to results found in bigger cohorts.
Authors
- Alexandre Harlé (ORCID: https://orcid.org/0000-0001-9548-6522)
- Andréa Witz (ORCID: https://orcid.org/0000-0002-1131-5193)
- Julie Dardare (ORCID: https://orcid.org/0000-0002-5315-1852)
- Margaux Betz (ORCID: https://orcid.org/0009-0003-2090-6918)
- Vincent Massard (ORCID: https://orcid.org/0009-0007-6690-3535)
- Pauline Gilson (ORCID: https://orcid.org/0000-0001-6735-563X)
- Romain Boidot (ORCID: https://orcid.org/0000-0001-9956-1737)
- Jean‐Louis Merlin (ORCID: https://orcid.org/0000-0001-8524-8897)
- Cassandra Michel
Institutions
- Centre National de la Recherche Scientifique (FR)
- Centre Georges François Leclerc (FR)
- Institut de Cancérologie de Lorraine (FR)
- Centre de Recherche en Automatique de Nancy (FR)
- Université de Lorraine (FR)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1016/j.tranon.2025.102315
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94