The Presence of Externalizing Diagnoses Increases the Risk of Suicidal Thoughts and Behaviors in Youth Enriched for Early-Onset Depression

Youth with comorbid depression and an externalizing disorder or externalizing symptoms of irritability or impulsivity may be at an elevated risk of STBs into early adolescence. These findings highlight the importance of early identification and treatment of externalizing disorders and symptoms in addition to treating depression when managing STBs in this population and provide additional potential treatment targets.