Comparative Analysis of Postoperative Radiotherapy Dose Escalation in Oral Cavity Cancer Patients with Positive Margins: A Propensity Score-Matched Study

Dose escalation to 66 Gy for PM during adjuvant RT for PO OCSCC can be used as an alternative strategy to reresection, especially in patients who have poor performance status, who have negative consent for surgery, and who have more than one adverse prognostic factor with comparable LC and toxicity as in the NM. However, further prospective studies are needed to establish its role as an alternative, which is highly unlikely in modern oncology practice, as PM patients are rarely seen in clinics currently with good surgical oncology practices.

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Publication Details

Journal
South Asian Journal of Cancer
Published
2025-02-04
DOI
https://doi.org/10.1055/s-0045-1802626
Primary Topic
Head and Neck Cancer Studies
Type
article
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0.00
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article

Comparative Analysis of Postoperative Radiotherapy Dose Escalation in Oral Cavity Cancer Patients with Positive Margins: A Propensity Score-Matched Study

Anil Kumar Tiwari, Rajesh Pasricha, Rashmi Sarawagi, A. Padmanabhan et al.
South Asian Journal of Cancer
Head and Neck Cancer Studies
article

Comparative Analysis of Postoperative Radiotherapy Dose Escalation in Oral Cavity Cancer Patients with Positive Margins: A Propensity Score-Matched Study

Anil Kumar Tiwari, Rajesh Pasricha, Rashmi Sarawagi, A. Padmanabhan, Saikat Das, Vipin Kharade, Raju Prajapati, Manish Gupta, Neelesh Shrivastava, Balaji Reddy
article en

Abstract

Dose escalation to 66 Gy for PM during adjuvant RT for PO OCSCC can be used as an alternative strategy to reresection, especially in patients who have poor performance status, who have negative consent for surgery, and who have more than one adverse prognostic factor with comparable LC and toxicity as in the NM. However, further prospective studies are needed to establish its role as an alternative, which is highly unlikely in modern oncology practice, as PM patients are rarely seen in clinics currently with good surgical oncology practices.

South Asian Journal of CancerVol. 14(02)
All India Institute of Medical Sciences Bhopal (IN), Post Graduate Institute of Medical Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 98%
Head and Neck Cancer Studies
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