The Effect of QT, QTc, and Tpe Interval on Outcome and Mortality in Syncope Patients

Abstract Syncope is a transient condition associated with disturbance of cerebral perfusion. Mortality is higher in cases of syncope of cardiac origin, which is observed in patients with arrhythmogenic findings on electrocardiogram (ECG). In this study, we plan to investigate the relationship of QT interval (QT), Corrected QT Interval (QTc), T peak end (Tpe), Tpe/QT, and Tpe/QTc measured on 12-lead ECGs of patients with mortality and outcomes of patients. Our study was conducted prospectively with syncope patients older than 18 years presenting to the emergency department of a tertiary teaching and research hospital. The demographic data, ECGs, laboratory data, and outcomes of the syncope patients were recorded and analyzed. Of the 80 syncope patients who participated in the study, 36% were women. The V5 interval of the syncope patients was significantly longer than that of the control group. When comparing the TpeV5/QTc rates of the patients, the syncope patients had significantly higher rates. In a categorical comparison, the Tpe times of the syncope patients were more frequently prolonged than those of the control group. The measurement of Tpe interval, which is prolonged in patients, appears as a parameter for syncope. The prolongation of the Tpe time observed in lead V5 of the ECG requires a closer follow-up of the patients, especially during the follow-up in daily practice, which represents an important part of the emergency admissions.