Bodyweight and Absolute Lymphocyte Count-Based Dosing of Rabbit Anti-thymocyte Globulin Results in Early CD4+ Immune Reconstitution in Patients with Inborn Errors of Metabolism Undergoing Umbilical Cord Blood Transplantation
In patients with IEM, individualized dosing of rATG was associated with a robust and early CD4<sup>+</sup> immune reconstitution, with no graft failures and low GVHD incidence.
Authors
- Connor Demorest (ORCID: https://orcid.org/0000-0002-3054-6288)
- Jaap Jan Boelens (ORCID: https://orcid.org/0000-0003-2232-6952)
- Daniel Drozdov (ORCID: https://orcid.org/0000-0002-3010-7525)
- Troy C. Lund (ORCID: https://orcid.org/0000-0001-9174-8919)
- Paul J. Orchard (ORCID: https://orcid.org/0000-0001-9426-1292)
- Ashish O. Gupta
- Qing Ping Cao (ORCID: https://orcid.org/0000-0002-5844-2376)
- Susan E. Long (ORCID: https://orcid.org/0000-0002-2730-451X)
- Jessica Kandil
Institutions
- University of Minnesota (US)
- Memorial Sloan Kettering Cancer Center (US)
- University Children's Hospital Zurich (CH)
- University of Minnesota Medical Center (US)
- Kantonsspital Aarau (CH)
- University of Minnesota Children's Hospital (US)
Publication Details
- Journal
- Transplantation and Cellular Therapy
- Published
- 2025-02-05
- DOI
- https://doi.org/10.1016/j.jtct.2025.01.893
- Citations
- 1
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 1.77