Effect of parecoxib on postoperative delirium in patients with hyperlipidemia: a randomized, double-blind, single-center, superiority trial
Parecoxib may help in reducing the hyperlipidemia-related postoperative delirium incidence. The effective anti-inflammatory activity of prostaglandin endoperoxide synthase-2 inhibition by parecoxib and postoperative pain control may be important mechanisms for preventing postoperative delirium.
Authors
- Mark Coburn (ORCID: https://orcid.org/0000-0002-7930-0270)
- Tao Peng (ORCID: https://orcid.org/0000-0002-0813-931X)
- Ana Kowark (ORCID: https://orcid.org/0000-0002-7433-8675)
- Yue Zhao (ORCID: https://orcid.org/0000-0002-1589-6351)
- Yuling Tang (ORCID: https://orcid.org/0000-0003-0810-208X)
- Daiying Zhang (ORCID: https://orcid.org/0000-0002-4316-1133)
- Zeng Daojun
- Duan Xiaoxia
- Xu Yingzhe
- Zhang Qixin
Institutions
- University Hospital Bonn (DE)
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1097/js9.0000000000002286
- Citations
- 11
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 17.00
Funders
- Southwest Medical University