Patients With Irritable Bowel Syndrome With Constipation From the IBS in America 2024 Real-World Survey Experience Burdensome Symptoms Beyond Constipation.

were self-reported, and only participants with online access were able to participate.Because the study was undertaken during the COVID-19 pandemic, this may have affected outcomes.Further, some data were unable to be adequately captured in these surveys, such as the length of time that medication was taken before discontinuation and reasons for nonadherence to daily treatment.As a result, additional evaluation is required to better understand whether the self-reported lack of abdominal and bowel symptom improvement was owing to premature discontinuation of treatment or lack of adherence.Finally, the authors noted that the frequency of prescribed medications is lower than the frequency of over-the-counter medications, which may limit the generalizability of the results.