Prognostic factors and preoperative therapy in resectable intrahepatic cholangiocarcinoma

Negative prognostic factors for resectable IHCC are lesion size ≥8 cm, intrahepatic and regional metastases, invasion into neighboring structures, R1 resection. Combination of negative factors worsened prognosis. Adjuvant therapy improved postoperative outcomes. Preoperative therapy may be advisable in case of negative factors and high risk of R1 resection.

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Publication Details

Journal
Pirogov Russian Journal of Surgery
Published
2025-02-04
DOI
https://doi.org/10.17116/hirurgia20250115
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic factors and preoperative therapy in resectable intrahepatic cholangiocarcinoma

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Prognostic factors and preoperative therapy in resectable intrahepatic cholangiocarcinoma

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article en

Abstract

Negative prognostic factors for resectable IHCC are lesion size ≥8 cm, intrahepatic and regional metastases, invasion into neighboring structures, R1 resection. Combination of negative factors worsened prognosis. Adjuvant therapy improved postoperative outcomes. Preoperative therapy may be advisable in case of negative factors and high risk of R1 resection.

Pirogov Russian Journal of Surgery(1)
Russian Cancer Research Center NN Blokhin (RU), Russian Scientific Center of Radiology and Surgical Technologies (RU)
Good health and well-being
Openalex Percentile: Top 97%
Cholangiocarcinoma and Gallbladder Cancer Studies
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