Comparative Efficacy of Deuterium and Alum as Adjuvants to Enhance the Shelf Life of Hemorrhagic Septicemia Vaccines

One of the difficult problems in preserving the quality of the products from manufacture till it reaches the end consumers is the preservation of the products. Serum immunoglobulins, plasma fractions, clinical samples, including tissues and bodily fluids, live attenuated virus vaccines, and clinical samples are among the materials that typically need to be maintained in a cold chain to maintain their quality. In the present study the thermostable quality of the generated subunit vaccine was assessed by keeping the recombinant vaccine for 180 days at 4ºC to 37ºC. It was contrasted with an HS alum precipitated vaccine under the same conditions. The present study in comparison of overall humoral immune response against recombinant OmpH deuterium vaccine and HS alum precipitated vaccine at 37ºC. The antibody titres of deuterium with OmpH and HS alum were at par with each other.