Evaluating Alcoholic Liver Biomarkers for Rehabilitation Admission during the COVID-19 Period in Kenya

Consumption of alcohol is a practice world over that dates back to 10,000 Before Christ. Evaluation on the damages caused by the alcohol on the human organs such as the liver is paramount. There is no direct evaluation to liver parenchyma before admission rather blood samples are evaluated to show damage or no damage to the liver cells. The outcome of the blood samples denotes the health status of the liver cells before admission. Alcohol biomarkers are usually elevated when there is damage to the liver parenchyma. This was a quantitative descriptive cross-sectional study. Purpose sampling was used to select two Counties with the highest number of alcohol consumers. Simple Random sampling method was used to select participants for liver biomarkers. Participants were requested to consent for blood donation and confidentiality was maintained. Blood samples collected were separated for serum and cells using centrifuge within one hour after donation. The samples were transported for storage using cool boxes and temperature was maintained between -8- and +8-degrees during transportation. The blood samples were stored at -8 and +8 degrees in the deep freezer. Majority (97%) of the participants had alanine aminotransferase levels of 41 to 80 IU/L. Eighty eight percent of the participants had aspartate aminotransferase elevated to between 35 and 68 IU/L. Gamma Glutamyl aminotransferase was elevated in all of the participants while alanine phosphatase was elevated in 99% of the participants. Most participants had elevated liver biomarkers before admission to rehabilitation centre.

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Publication Details

Journal
Journal of Advances in Medicine and Medical Research
Published
2025-02-04
DOI
https://doi.org/10.9734/jammr/2025/v37i25724
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Evaluating Alcoholic Liver Biomarkers for Rehabilitation Admission during the COVID-19 Period in Kenya

George Njoroge, Stanley Kinge Waithaka, Ezekiel Onyonka Mecha, Catherine Mwenda
Journal of Advances in Medicine and Medical Research
Liver Disease Diagnosis and Treatment
article

Evaluating Alcoholic Liver Biomarkers for Rehabilitation Admission during the COVID-19 Period in Kenya

George Njoroge, Stanley Kinge Waithaka, Ezekiel Onyonka Mecha, Catherine Mwenda
article en

Abstract

Consumption of alcohol is a practice world over that dates back to 10,000 Before Christ. Evaluation on the damages caused by the alcohol on the human organs such as the liver is paramount. There is no direct evaluation to liver parenchyma before admission rather blood samples are evaluated to show damage or no damage to the liver cells. The outcome of the blood samples denotes the health status of the liver cells before admission. Alcohol biomarkers are usually elevated when there is damage to the liver parenchyma. This was a quantitative descriptive cross-sectional study. Purpose sampling was used to select two Counties with the highest number of alcohol consumers. Simple Random sampling method was used to select participants for liver biomarkers. Participants were requested to consent for blood donation and confidentiality was maintained. Blood samples collected were separated for serum and cells using centrifuge within one hour after donation. The samples were transported for storage using cool boxes and temperature was maintained between -8- and +8-degrees during transportation. The blood samples were stored at -8 and +8 degrees in the deep freezer. Majority (97%) of the participants had alanine aminotransferase levels of 41 to 80 IU/L. Eighty eight percent of the participants had aspartate aminotransferase elevated to between 35 and 68 IU/L. Gamma Glutamyl aminotransferase was elevated in all of the participants while alanine phosphatase was elevated in 99% of the participants. Most participants had elevated liver biomarkers before admission to rehabilitation centre.

Journal of Advances in Medicine and Medical ResearchVol. 37(2)
University of Nairobi (KE)
Openalex Percentile: Top 97%
Liver Disease Diagnosis and Treatment
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Evaluating Alcoholic Liver Biomarkers for Rehabilitation Admission during the COVID-19 Period in Kenya — George Njoroge, Stanley Kinge Waithaka, et al. · Journal of Advances in Medicine and Medical Research (2025) | TGRS Research Map | TGRS