Functional connectivity-based compensation in the brains of non-demented older adults and the influence of lifestyle: A longitudinal 7-year study
There are widespread changes in structural and functional connectivity in older adults. Despite the trend of dedifferentiation in functional connectivity, we detected both direct and indirect compensatory subnetworks that mitigated the decline in cognitive performance. The degree of compensation was influenced by demographic, biological, and lifestyle factors.
Authors
- Lutz Jäncke (ORCID: https://orcid.org/0000-0003-2110-9067)
- Isabel Hotz (ORCID: https://orcid.org/0000-0002-7938-0688)
- Susan Mérillat (ORCID: https://orcid.org/0000-0002-0566-088X)
- Pascal Frédéric Deschwanden (ORCID: https://orcid.org/0000-0002-1846-8504)
Institutions
- Union Bank of Switzerland (CH)
- University of Zurich (CH)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121075
- Citations
- 4
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- Velux Stiftung