Can Baseline Urodynamic Findings Predict the Outcomes and Complications of Intravesical Injections of Onabotulinum Toxin A for Overactive Bladder?
Successful outcomes (based on the self-reported PGI-I score) were more likely in women and correlated positively with the increased duration of voiding detrusor contraction, but no other urodynamic parameters. The risk of developing de novo need to catheterize correlated with patient reported benefit, but not with any baseline urodynamic findings. We did not find pre-existing bladder outflow obstruction, concurrent stress urinary incontinence or complex previous surgical history to adversely affect treatment success.
Authors
- Habiba Yasmin (ORCID: https://orcid.org/0000-0003-4272-7526)
- Kristina Aleksejeva (ORCID: https://orcid.org/0000-0002-2913-5334)
- Richard G. Axell (ORCID: https://orcid.org/0000-0001-8591-0174)
- Jeremy Ockrim (ORCID: https://orcid.org/0000-0003-1208-9826)
- Mahreen H. Pakzad (ORCID: https://orcid.org/0000-0001-9672-8132)
- Gemma Scrimgeour (ORCID: https://orcid.org/0000-0002-8597-6437)
- Tamsin Jillian Greenwell (ORCID: https://orcid.org/0000-0002-9074-7604)
Institutions
- University College Hospital (GB)
- Royal Bournemouth Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- Neurourology and Urodynamics
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1002/nau.70000
- Citations
- 3
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 5.51