Pulmonary Nuclear protein in Testis (NUT) carcinoma: clinical, molecular characteristics, and treatment strategies

Advanced molecular techniques are critical for diagnosing pulmonary NUT carcinoma, but survival outcomes remain poor. Surgical resection with adjuvant therapy offers better outcomes for early-stage patients, while chemotherapy and immunotherapy show limited efficacy in metastatic cases due to the tumor's aggressive behavior. Early detection and innovative therapies are essential for improving outcomes.

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Publication Details

Journal
BMC Cancer
Published
2025-02-04
DOI
https://doi.org/10.1186/s12885-025-13593-3
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
0.00

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article

Pulmonary Nuclear protein in Testis (NUT) carcinoma: clinical, molecular characteristics, and treatment strategies

Jingjing Qu, Yan‐Ping Zhu, Zhen Chen, Qian Shen et al.
BMC Cancer
Protein Degradation and Inhibitors
article

Pulmonary Nuclear protein in Testis (NUT) carcinoma: clinical, molecular characteristics, and treatment strategies

Jingjing Qu, Yan‐Ping Zhu, Zhen Chen, Qian Shen, Jinyan Huang
article en

Abstract

Advanced molecular techniques are critical for diagnosing pulmonary NUT carcinoma, but survival outcomes remain poor. Surgical resection with adjuvant therapy offers better outcomes for early-stage patients, while chemotherapy and immunotherapy show limited efficacy in metastatic cases due to the tumor's aggressive behavior. Early detection and innovative therapies are essential for improving outcomes.

BMC CancerVol. 25(1)
Zhejiang Medicine (China) (CN), First Affiliated Hospital Zhejiang University (CN), Zhejiang University (CN)
Natural Science Foundation of Zhejiang Province
Zero hunger
Openalex Percentile: Top 98%
Protein Degradation and Inhibitors
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Pulmonary Nuclear protein in Testis (NUT) carcinoma: clinical, molecular characteristics, and treatment strategies — Jingjing Qu, Yan‐Ping Zhu, et al. · BMC Cancer (2025) | TGRS Research Map | TGRS