Newly identified single-nucleotide polymorphism associated with the transition from nonalcoholic fatty liver disease to liver fibrosis: results from a nested case-control study in the UK biobank
Our research highlights a significant association of SAMM50-rs2073080 with the progression of NAFLD to hepatic fibrosis, and the <i>in vitro</i> experiments further corroborated these findings.
Authors
- Jing Hao Wang
- Yitong Ling
- Sha Sha Li (ORCID: https://orcid.org/0000-0001-8544-9242)
- Yan Chun Chen
- Jun Lyu (ORCID: https://orcid.org/0000-0002-2237-8771)
- Xiaoyu Zhang (ORCID: https://orcid.org/0000-0002-1561-5273)
- Duo Feng (ORCID: https://orcid.org/0000-0002-1401-0408)
- Siyu Xiang (ORCID: https://orcid.org/0009-0004-9732-8156)
- Yu Xuan Yang
Institutions
- Qingdao University (CN)
- Sun Yat-sen University (CN)
- Jinan University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Qingdao University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-02-03
- DOI
- https://doi.org/10.1080/07853890.2025.2458201
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35