Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells
Macrophage-derived miR-194 promotes cisplatin resistance in GC cells by inhibiting apoptosis through PTEN downregulation. These findings provide new insights and theoretical backing for clinical treatment strategies in GC.
Authors
- Xinjian Zhu (ORCID: https://orcid.org/0000-0001-8386-4952)
- Qiongyan Zhang (ORCID: https://orcid.org/0000-0001-9093-3418)
- Yue Sun (ORCID: https://orcid.org/0000-0003-2143-5516)
- Xiangyu Su (ORCID: https://orcid.org/0000-0001-6486-3110)
- Yi Zhou (ORCID: https://orcid.org/0000-0001-7300-0173)
- Jing Wang (ORCID: https://orcid.org/0000-0002-3224-3993)
Institutions
- Zhongda Hospital Southeast University (CN)
- Hanzhong People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-02-04
- DOI
- https://doi.org/10.1186/s40001-025-02329-5
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61